%R doi:10.1186/s12883-022-02834-8 %L katalog9279 %N 322 %I BioMed Central Ltd. %D 2022 %K moderna; vaccine; acute dizziness; mental alteration; encephalopathy %V 22 %T ACUTE DIZZINESS AND MENTAL ALTERATION ASSOCIATED WITH MODERNA COVID-19 VACCINE: A CASE REPORT %J Journal of BMC Neurology %P 1-4 %A Rizaldy Taslim Pinzon %X Background Due to a rising number of COVID-19 cases, the Indonesian government implemented public health programs to lower the rate. Since January 2021, one of the government’s primary policies has been the COVID-19 immunization program. Recently, the Moderna messenger ribonucleic acid (mRNA) vaccine is one of the COVID-19 vaccines used in Indonesia. Based on some research, Moderna has possible side effects throughout the body, including neurological symptoms. Case presentation We describe a 39-year-old female with uncontrolled hypertension who showed behavioral change, communication difficulty, social withdrawal, and a confused state within 7 days from getting her first dose of the Moderna vaccine. The patient had a history of febrile convulsion in childhood. An increase of neutrophil-to-lymphocyte ratio (16.9) and C-reactive protein level (31.75 mg/L) indicates ongoing inflammation. Head CT scan shows no abnormalities. She received ceftriaxone, citicoline, and methylprednisolone. The patient was discharged on the seventh day and completely recovered 1 week later. This study is the first case report of encephalopathy following the administration of the Moderna COVID-19 vaccine reported in Indonesia up to our knowledge. Conclusion Encephalopathy related to the Moderna COVID-19 vaccine should be acknowledged as an adverse effect of the Moderna COVID-19 vaccine.