eprintid: 9235
rev_number: 9
eprint_status: archive
userid: 2098
dir: disk0/00/00/92/35
datestamp: 2024-09-13 03:51:35
lastmod: 2024-09-13 03:51:35
status_changed: 2024-09-13 03:51:35
type: article
metadata_visibility: show
contact_email: repository@staff.ukdw.ac.id
creators_name: , Rizaldy Taslim Pinzon
creators_name: , Tillandsia Filli Folia Primastuti
creators_id: 0517057601
title: NOCARDIA LYMPHADENITIS AND ENCEPHALITIS IN IMMUNOCOMPROMISED PATIENT: A CASE REPORT
ispublished: pub
subjects: RC0321
divisions: fak_kedokteran
full_text_status: public
keywords: Encephalitis, HIV, Nocardia sp., CD4+ 7 cells, colli lesions, HIV-positive
abstract: Background:
Nocardiosis-related HIV usually appears in immunocompromised patients, which is caused by Nocardia sp. Although a number of reports describe pulmonary forms of nocardiosis in HIV-positive patients, lymphadenitis and encephalitis due to this organism are rare entities. Our preliminary search has only found a few cases reported in the literature. Unless investigations like gram stain and culture for Nocardia are specifically done, the infection is often mistaken for tuberculosis. We have herein reported a case of Nocardia lymphadenitis and encephalitis in an HIV-positive patient.

Case Presentation:
A 33-year-old male presented fever, progressive weakness in the right side of the body, multiple lesions on the oral cavity, and left colli lesions. Physical examination found GCS as E4 M6 V uncounted, hypertonic and increased physiology reflexes on the right extremity without pathologic reflexes, meningeal signs, and all cranial nerves as normal. The laboratory test result was HIV-positive with CD4+ 7 cells/μL and Nocardia sp. on histopathology. A plain head computed tomography (CT) scan showed a hypodense lesion in the fronto-temporo-parieto-occipital sinistra region, and vasogenic edema. The patient was administered antiretroviral (ARV) therapy and antibiotics for nocardiosis lymphadenitis.

Conclusion:
A rare case of Nocardia lymphadenitis has been reported in this paper, and the physician must be aware of nocardiosis in HIV patients with neurological deficits.
date: 2023-10-30
publication: The Open Neurology Journal
volume: 17
publisher: Bentham Science Publishers B.V.
pagerange: 1-4
id_number: doi:10.2174/011874205X254011230922043119
refereed: TRUE
issn: 1874-205X
official_url: http://dx.doi.org/10.2174/011874205X254011230922043119
funders: drpinzon17@gmail.com
citation:   Rizaldy Taslim Pinzon and Tillandsia Filli Folia Primastuti  (2023) NOCARDIA LYMPHADENITIS AND ENCEPHALITIS IN IMMUNOCOMPROMISED PATIENT: A CASE REPORT.  The Open Neurology Journal, 17.  pp. 1-4.  ISSN 1874-205X     
document_url: https://katalog.ukdw.ac.id/9235/1/Nocardia%20Lymphadenitis%20and%20Encephalitis%20in%20Immunocompromised%20Patient.pdf