eprintid: 9187
rev_number: 12
eprint_status: archive
userid: 2098
dir: disk0/00/00/91/87
datestamp: 2024-09-12 06:40:20
lastmod: 2024-09-12 06:40:20
status_changed: 2024-09-12 06:40:20
type: article
metadata_visibility: show
contact_email: repository@staff.ukdw.ac.id
creators_name: , Rizaldy Taslim Pinzon
creators_id: 0517057601
title: CLINICAL RECOMMENDATIONS FOR THE USE OF NEUROTROPIC B VITAMINS (B1, B6, AND B12) FOR THE MANAGEMENT OF PERIPHERAL NEUROPATHY: CONSENSUS FROM A MULTIDISCIPLINARY EXPERT PANEL
ispublished: pub
subjects: RC0321
divisions: fak_kedokteran
full_text_status: public
abstract: Introduction: Peripheral neuropathy (PN) is an insidious disease that is often asymptomatic during the early stages but which can have a significant impact on quality of life at later stages when nerve damage occurs. There is currently no guidance on the use of neurotropic B vitamins (B1, B6, and B12) for the management of asymptomatic and symptomatic PN.

Objective: To provide guidance to primary care physicians on an integrated approach to managing PN with neurotropic B vitamins (B1, B6, and B12).

Materials and methods: A multidisciplinary panel of eight experts participated in an iterative quasi-anonymous Delphi survey consisting of two rounds of questions and a virtual meeting. A literature review formed the basis of the survey questions. The first round included multiple select, qualitative, and Likert Scale questions; the subsequent round consisted of 2-point scale (agree or disagree) questions that sought to develop consensus-based statements refined from the first round and recommendations derived from discussions during the virtual expert panel meeting.

Results: Clinical recommendations for the use of neurotropic B vitamins (B1, B6, and B12) have been developed for the prevention of PN progression or to delay onset in patients at high risk of developing PN. Recommendations have also been provided for the assessment of PN etiology and considerations for the use of loading dose (high dose) and maintenance dose (lower dose) of these neurotropic B vitamins (B1, B6, and B12).

Conclusion: These clinical recommendations provide an initial step towards formulating comprehensive guidelines for the early and long-term management of PN with neurotropic B vitamins (B1, B6, and B12) and move beyond addressing only neuropathic pain associated with the late stages of PN.
date: 2023-07
publication: Journal of Association of Physicians of India
volume: 71
number: 7
publisher: Journal of Association of Physicians of India
pagerange: 94-98
id_number: DOI: 10.59556/japi.71.0290
refereed: TRUE
issn: 0004 - 5772
official_url: https://doi.org/10.59556/japi.71.0290
funders: drpinzon17@gmail.com
citation:   Rizaldy Taslim Pinzon  (2023) CLINICAL RECOMMENDATIONS FOR THE USE OF NEUROTROPIC B VITAMINS (B1, B6, AND B12) FOR THE MANAGEMENT OF PERIPHERAL NEUROPATHY: CONSENSUS FROM A MULTIDISCIPLINARY EXPERT PANEL.  Journal of Association of Physicians of India, 71 (7).  pp. 94-98.  ISSN 0004 - 5772     
document_url: https://katalog.ukdw.ac.id/9187/1/Clinical%20Recommendations%20for%20the%20use%20of%20Neurotropic%20B%20vitamins.pdf