eprintid: 9140 rev_number: 9 eprint_status: archive userid: 2098 dir: disk0/00/00/91/40 datestamp: 2024-09-12 05:09:43 lastmod: 2024-09-12 05:09:43 status_changed: 2024-09-12 05:09:43 type: article metadata_visibility: show contact_email: repository@staff.ukdw.ac.id creators_name: , Aniek Prasetyaningsih creators_name: , Vinsa Cantya Prakasita creators_id: 0518096402 creators_id: 0510069201 title: THE EFFECT OF SHRIMP SHELL (LITOPENAEUS VANNAMEI) EXTRACT ON TESTICULAR PARAMETERS OF STREPTOZOTOCININDUCED DIABETIC RATS ispublished: pub subjects: QL subjects: R1 divisions: fak_biot full_text_status: public keywords: Astaxanthin, Diabetes mellitus, Fertility, Seminiferous tubule, Testis abstract: Diabetes mellitus (DM) is a chronic metabolic disorder that has become a major health problem worldwide. Reproductive dysfunction is one of the main complications of DM, particularly in men. However, as is known, shrimp shell extract contains nutrients, such as astaxanthin, that affect reproductive traits. The present study aimed to evaluate the effect of shrimp shell extract on the volume, weight, and histological features of the testes of a DM rat model. Fifteen adult male rats were randomly divided into three groups. Group A (n = 5) was a healthy control group, group B (n = 5) was a DM control group, and group C (n = 5) was a DM group treated with shrimp shell extract. Rats in groups B and C were treated with streptozotocin to induce DM. Rats in group C were given shrimp shell extract at 25 mg/kg body weight for 30 consecutive days after DM induction. Testicles were collected and submitted to dimension, weight, and histological examinations. The testicle volume and weight of rats in group C were significantly higher and heavier, respectively, than rats in group B and did not differ from rats in group A. The seminiferous tubule diameter of rats in group C was significantly larger than rats in group B and did not differ from rats in group A. Rats in group B had a lower testicle volume and lighter testicle weight as well as a shorter seminiferous tubule diameter than rats in groups A and C. In conclusion, shrimp shell extract could improve male fertility parameters in a DM rat model. However, the mechanism of action needs to be studied further date: 2023-03-25 publication: World’s Veterinary Journal volume: 13 number: 1 publisher: SCIENCELINE State of Erzurum, Turkey id_number: doi:10.54203/scil.2023.wvj15 refereed: TRUE issn: 2322-4568 official_url: https://dx.doi.org/10.54203/scil.2023.wvj15 funders: vinsa.cantya.p@staff.ukdw.ac.id citation: Aniek Prasetyaningsih and Vinsa Cantya Prakasita (2023) THE EFFECT OF SHRIMP SHELL (LITOPENAEUS VANNAMEI) EXTRACT ON TESTICULAR PARAMETERS OF STREPTOZOTOCININDUCED DIABETIC RATS. World’s Veterinary Journal, 13 (1). ISSN 2322-4568 document_url: https://katalog.ukdw.ac.id/9140/1/The%20Effect%20of%20Shrimp%20Shell%20%28Litopenaeus%20vannamei%29%20Extract%20.pdf