eprintid: 9057
rev_number: 8
eprint_status: archive
userid: 2098
dir: disk0/00/00/90/57
datestamp: 2024-09-03 07:52:30
lastmod: 2024-09-03 07:52:30
status_changed: 2024-09-03 07:52:30
type: article
metadata_visibility: show
contact_email: repository@staff.ukdw.ac.id
creators_name: , Rizaldy Taslim Pinzon
creators_name: , Manengku Nasahu Saben Nara
creators_name: , Esdras Ardi Pramudita
creators_id: 41180271
title: CHARACTERISTICS OF THE PLATELET PROFILE AS A PREDICTOR OF 30-DAY CLINICAL OUTCOME IN ISCHEMIC STROKE PATIENTS
ispublished: pub
subjects: R1
subjects: RC0321
divisions: ar_non_ukdw
full_text_status: public
keywords: ischemic stroke, PDW, MPV, disability
abstract: Objective. Investigate the relationship between platelet profiles, in this case PDW and MPV at hospital admission, which can be predictors of clinical outcome 30 days after ischemic stroke. Methods. This research is an analytic study with a retrospective cohort method. Secondary data in the form of medical records at the neuro polyclinic of Bethesda Hospital Yogyakarta in 2019 - 2020. The number of subjects was 74, grouped as good outcome (mRS 0-2) and poor outcome (mRS 3-6). Data analysis used was t-test, Pearson’s test, Fisher’s test, ROC, and multivariable logistic regression model. Results. In this study, both PDW (p = 0.982) and MPV (p = 0.174) were not significantly associated (p > 0.05) with poor outcomes on the chi-square test. ROC curve analysis showed that the PDW cutoff value was >11.1 fl [(Area Under Curve (AUC) ROC was 0.638, with 95% CI = 0.518-0.746, and p-value 0.835)] and the MPV cutoff value was ≤9,8 fl [(Area Under Curve (AUC) ROC was 0.521, with 95% CI = 0.402-0.639, and p-value 0.137)] which was also not statistically significant (p > 0.05). From these results, multivariable logistic regression analysis was performed which found that MPV ≤9,8 fl was associated with a small 30-day clinical outcome [(Odds Ratio (OR) = 0.110, 95% CI = 0.013-0.953, p = 0.007)]. While PDW >11.1 fl did not have a significant relationship after regression analysis was carried out where p > 0.05 was obtained. Conclusion. Increased PDW and MPV values at hospital admission did not increase the risk of 30-day disability in ischemic stroke patients.
date: 2023-03-28
date_type: published
publication: Romanian Journal of Neurology
volume: 22
number: 1
publisher: Amaltea Medical Publishing House
pagerange: 11-15
refereed: TRUE
issn: 1843-8148
official_url: https://rjn.com.ro/articles/2023.1/RJN_2023_1_Art-10.pdf
funders: drpinzon17@gmail.com
citation:   Rizaldy Taslim Pinzon and Manengku Nasahu Saben Nara and Esdras Ardi Pramudita  (2023) CHARACTERISTICS OF THE PLATELET PROFILE AS A PREDICTOR OF 30-DAY CLINICAL OUTCOME IN ISCHEMIC STROKE PATIENTS.  Romanian Journal of Neurology, 22 (1).  pp. 11-15.  ISSN 1843-8148     
document_url: https://katalog.ukdw.ac.id/9057/1/Characteristics%20of%20the%20platelet%20profile%20as%20a%20predictor%20of%2030-day%20clinical%20outcome.pdf